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Microsoft Word - Hamad_130809_proof.doc
CD4+
CD8+
CD4+CD8+
Naïve Controls 22.6 + 2.3 6.6 + 0.9 15.1 + 1.9 2.3 + 0.7
Day 7 30.1 + 3.0 12.4 + 1.5 16.7 + 2.4 1.8 + 0.5 Day 14 44.5 + 3.6 20.3 + 3.8 21.0 + 2.1 3.2 + 0.6 Day 21
41.3 + 4.2 8.7 + 2.1 [...] cell numbers expressing these rear- rangements. In cells from both tissues, TCRVβs 3.1, 5.1, 5.3, 8.1, 8.2, 8.3, 9, 19 and 20 were consistently low or absent (data not shown). With regard to vaginal T cells [...] infection (Figure 4, lower panel) extensive rearrangement of TCRVβs 1, 4, 6, 8.3, 10, 13, 14 and 18 was evident. TCRVβs 5.1, 8.1 and 8.3 were well represented in vaginal T cells of experimental mice at day 14 …