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octanes (8)
Figure 4: Synthetic route to pyrrolidine type 3,7diazabicyclo [3.3.0] octanes (8)
Methyl-2-benzyl-4-(5-methyl-2-furyl)- 6,8-dioxo-7-phenyl-3,7-diazabicyclo[3.3.0] octane-2-carboxylate (8c)
L-p [...] and 2.05 (dd, 1H, J = 9.2, 6.4 Hz, CH(H)CH(CH3)2], 3.46 (d, 1HC, J = 8.4 Hz), 3.72 (dd, 1HB, J = 8, 6.8 Hz), 4.76 (d, 1HA, J = 4.8 Hz), 6.95-7.35 (m, 10H, 2C6H5); IR υmax (nujol) 3369, 3326, 2355, 1772 [...] 10
ABSTRACT
Pyrrolidines type 2,4-disubstituted (alkyl, aryl or heteroaryl)-6,8-dioxo-3,7-diazabicyclo [3.3.0] octanes (8a-d) were successfully synthesized by an efficient one pot 1,3-dipolar cycloaddition …