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of large libraries for compound confirmation and purity assessment. By simulation with SIMION v. 7.0 it was proved that the configuration of the three stage differential pump system and the Einzel lens [...] have unique benefits for volatile organic compounds analysis. The detection limits are in the range of 0.8 µg/L for acetone, 8.6 µg/L for ethanol and 17.2 µg/L for benzene with direct permeation sampling. …