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Draft version, October 30, 2006
activated tolerance, inducing long-lasting CD8+ cells. Finally, failure to limit CD8+ cells leads to autoreactivity. In conclusion, non-T-cells balance tolerant CD8+ T-cells and prevent graft rejection by naïve [...] cell therapy. In the CABG + cell therapy group, LVEF increased by almost 10 % from 37.4±8.4 % at baseline to 47.1±8.3 % at 6 months, whereas patients treated by CABG were characterized by a gain in ejection [...] Cancer Research Center, Heidelberg) introduced the idea that tolerance could also be mediated by CD8+
cells and not only CD4+ cells. His talk focused on peripheral T-cell tolerance in the developing immune …